Publications

Peer-reviewed work from the lab and its principal investigator. This list updates automatically from PubMed.

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27 publications · updated 5 October 2026

2025

In vivo multiplexed modeling reveals diverse roles of the TBX2 subfamily and Egr1 in Kr as-driven lung adenocarcinoma

Khalil A, Dinh T, Parks M, Obeng RC, Gryder B, Kresak A, Wang Y, Maltas J, Bedrock M, Wei X, Faber Z, et al.

Genes & diseases · PMID 41705258 · DOI

In Vivo Multiplexed Modeling Reveals Diverse Roles of the TBX2 Subfamily and Egr1 in Ras -Driven Lung Adenocarcinoma

Khalil A, Dinh T, Parks M, Obeng RC, Gryder B, Kresak A, Wang Y, Maltas J, Bedrock M, Wei X, Faber Z, et al.

bioRxiv : the preprint server for biology · PMID 40166332 · DOI

2024

Small-molecule disruption of androgen receptor-dependent chromatin clusters

Kohrt SE, Novak EJ, Tapadar S, Wu B, Strope J, Asante Y, Kim H, Chang MS, Gurdak D, Khalil A, Rood M, et al.

Proceedings of the National Academy of Sciences of the United States of America · PMID 39560645 · DOI

Editorial: Precision oncology in the era of CRISPR-Cas9 technology

Khalil A

Frontiers in genetics · PMID 39492881 · DOI

2023

Unveiling immune checkpoint regulation: exploring the power of in vivo CRISPR screenings in cancer immunotherapy

Wang Y, Khalil A, Kamar A, Du M, Dinh T, McFarland C, Wang Z

Frontiers in genetics · PMID 38162677 · DOI

Exploring the molecular landscape of NNK-induced transformation: A comprehensive genome-wide CRISPR/Cas9 screening

Dinh T, Rahm M, Wang Z, McFarland C, Khalil A

Genes & diseases · PMID 38450101 · DOI

Novel genes linked to Class II Division 1 malocclusion with mandibular micrognathism

El Chekie MR, Nemer G, Khalil A, Macari AT, Ghafari JG

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics · PMID 36581475 · DOI

2022

Weekly Nowcasting of New COVID-19 Cases Using Past Viral Load Measurements

Khalil A, Al Handawi K, Mohsen Z, Abdel Nour A, Feghali R, Chamseddine I, Kokkolaras M

Viruses · PMID 35891394 · DOI

2021

Mutational signatures in GATA3 transcription factor and its DNA binding domain that stimulate breast cancer and HDR syndrome

El-Assaad A, Dawy Z, Khalil A, Nemer G

Scientific reports · PMID 34815386 · DOI

Questioning the sex-specific differences in the association of smoking on the survival rate of hospitalized COVID-19 patients

Khalil A, Dhingra R, Al-Mulki J, Hassoun M, Alexis N

PloS one · PMID 34351990 · DOI

Congenital Heart Disease in Syrian Refugee Children: The Experience at a Tertiary Care Center in a Developing Country

Mostafa H, Rashed M, Azzo M, Tabbakh A, El Sedawi O, Hussein HB, Khalil A, Bulbul Z, Bitar F, El Rassi I, Arabi M

Pediatric cardiology · PMID 33738510 · DOI

The Digenic Causality in Familial Hypercholesterolemia: Revising the Genotype-Phenotype Correlations of the Disease

Kamar A, Khalil A, Nemer G

Frontiers in genetics · PMID 33519890 · DOI

2020

The Lebanese COVID-19 Cohort; A Challenge for the ABO Blood Group System

Khalil A, Feghali R, Hassoun M

Frontiers in medicine · PMID 33330542 · DOI

Founder Mutation in N Terminus of Cardiac Troponin I Causes Malignant Hypertrophic Cardiomyopathy

Fahed AC, Nemer G, Bitar FF, Arnaout S, Abchee AB, Batrawi M, Khalil A, Abou Hassan OK, DePalma SR, McDonough B, Arabi MT, et al.

Circulation. Genomic and precision medicine · PMID 32885985 · DOI

A novel TRAF3IP2 variant causing familial scarring alopecia with mixed features of discoid lupus erythematosus and folliculitis decalvans

Nemer G, El-Hachem N, Eid E, Hamie L, Bardawil T, Khalil S, El-Rassy I, Safi R, Khalil A, Abbas O, Shimomura Y, Kurban M

Clinical genetics · PMID 32350852 · DOI

Thalidomide-Revisited: Are COVID-19 Patients Going to Be the Latest Victims of Yet Another Theoretical Drug-Repurposing?

Khalil A, Kamar A, Nemer G

Frontiers in immunology · PMID 32574274 · DOI

Post-lingual non-syndromic hearing loss phenotype: a polygenic case with 2 biallelic mutations in MYO15A and MITF

Khalil A, Karroum SB, Barake R, Dunya G, Abou-Rizk S, Kamar A, Nemer G, Bassim M

BMC medical genetics · PMID 31898538 · DOI

The potential oncogenic role of the RAS-like GTP-binding gene RIT1 in glioblastoma

Khalil A, Nemer G

Cancer biomarkers : section A of Disease markers · PMID 32831193 · DOI

2019

A Cautious Note on Thalidomide Usage in Cancer Treatment: Genetic Profiling of the TBX2 Sub-Family Gene Expression is Required

Nemer G, Khalil A

Drug research · PMID 30934098 · DOI

Epigenetic Suppression of the T-box Subfamily 2 (TBX2) in Human Non-Small Cell Lung Cancer

Nehme E, Rahal Z, Sinjab A, Khalil A, Chami H, Nemer G, Kadara H

International journal of molecular sciences · PMID 30866410 · DOI

Non-familial cardiomyopathies in Lebanon: exome sequencing results for five idiopathic cases

Refaat MM, Hassanieh S, Ballout JA, Zakka P, Hotait M, Khalil A, Bitar F, Arabi M, Arnaout S, Skouri H, Abchee A, et al.

BMC medical genomics · PMID 30764827 · DOI

2018

Degenerated hair follicle cells and partial loss of sebaceous and eccrine glands in a familial case of axenfeld-rieger syndrome: An emerging role for the FOXC1/NFATC1 genetic axis

Hariri H, Kurban M, Al-Haddad C, Fahed AC, Poladian S, Khalil A, Abbas O, Arabi M, Bitar F, Nemer G

Journal of dermatological science · PMID 30514661 · DOI

Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes

Khalil A, Dekmak B, Boulos F, Kantrowitz J, Spira A, Fujimoto J, Kadara H, El-Hachem N, Nemer G

Frontiers in oncology · PMID 30425966 · DOI

2017

A Novel Mutation in FOXC1 in a Lebanese Family with Congenital Heart Disease and Anterior Segment Dysgenesis: Potential Roles for NFATC1 and DPT in the Phenotypic Variations

Khalil A, Al-Haddad C, Hariri H, Shibbani K, Bitar F, Kurban M, Nemer G, Arabi M

Frontiers in cardiovascular medicine · PMID 28979898 · DOI

TBX2 subfamily suppression in lung cancer pathogenesis: a high-potential marker for early detection

Khalil AA, Sivakumar S, Lucas FAS, McDowell T, Lang W, Tabata K, Fujimoto J, Yatabe Y, Spira A, Scheet P, Nemer G, Kadara H

Oncotarget · PMID 28978111 · DOI

A HAND to TBX5 Explains the Link Between Thalidomide and Cardiac Diseases

Khalil A, Tanos R, El-Hachem N, Kurban M, Bouvagnet P, Bitar F, Nemer G

Scientific reports · PMID 28469241 · DOI

AutoDock and AutoDockTools for Protein-Ligand Docking: Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1(BACE1) as a Case Study

El-Hachem N, Haibe-Kains B, Khalil A, Kobeissy FH, Nemer G

Methods in molecular biology (Clifton, N.J.) · PMID 28508374 · DOI